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Autophagy

Autophagy is a lysosomal degradation pathway for proteins and organelles that is essential for survival during nutrient starvation, cell growth, differentiation, development and homeostasis. It is a highly regulated process to maintain a balance between synthesis, degradation and recycling of cellular components. The most well-known mechanism of autophagy involves the formation of a membrane around a targeted region of the cell membrane. The resultant vesicle then fuses with a lysosome and leads to the degradation of its contents.

In principle autophagy provides an adaptive role to protect organisms against diverse pathologies, including cancer, neurodegeneration, bacterial and viral infections, aging and heart disease. However, malfuction of autophagy may actually contribute to the development of a desease.

Everest Biotech has developed several antibodies to proteins involved in the complex network of this pathway, please view our autophagy products below, search our website or view our polyclonal antibody production services and custom antibody services.
 

Antibodies for Autophagy

Everest code Principal name Applications Tested Species reactivity Size available
EB07893 Goat Anti-ATG16L1 Antibody Pep-ELISA, WB Human, Mouse, Rat. Dog 100µg/200µl
EB09223 Goat Anti-ATG4D Antibody Pep-ELISA Human, Mouse, Rat, Dog, Pig 100µg/200µl
EB08862 Goat Anti-ATG5 Antibody Pep-ELISA Human, Mouse, Cow, Horse 100µg/200µl
EB05486 Goat Anti-BAG3 / BIS/ CAIR1 Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB05158 Goat Anti-BIF-1 / SH3GLB1 Antibody Pep-ELISA, WB, IHC Human, Mouse, Rat, Dog, Cow 100µg/200µl
EB08008 Goat Anti-Cxcr4b (zebrafish) Antibody Pep-ELISA Zebrafish 100µg/200µl
EB06140 Goat Anti-MUNC18 / STXBP1 (isoform a) Antibody Pep-ELISA, WB, IHC Human, Mouse 100µg/200µl
EB07895 Goat Anti-NCF4 / P40PHOX Antibody Pep-ELISA, WB, IHC Human, Dog 100µg/200µl
EB05909 Goat Anti-SNX18 / SNAG1 Antibody Pep-ELISA, WB Human 100µg/200µl
EB07213 Goat Anti-STAM2 Antibody Pep-ELISA, WB Human, Mouse, Dog 100µg/200µl