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Goat Anti-ATP6IP2 / Renin receptor Antibody - Trial (EB06118-T)
| Code | Name | Applications | Availability | Size | Species reactivity | Price | Grade | |
|---|---|---|---|---|---|---|---|---|
| EB06118-T | Goat Anti-ATP6IP2 / Renin receptor Antibody - Trial | Pep-ELISA, WB, IHC |  |
20µg specific antibody in 40µl | Human, Mouse, Rat, Cow | $105.00 |  |
|
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$40.00: Overnight shipping to United States of America
Sent via overnight courier arrives approximately next day to mainland USA. Please note that your order will be processed and invoiced by our US partner Abcore LLC. Order offlineNow shipping direct to US customers! 99% of products are held in stock for immediate shipment, see individual product pages for availability. Please order through the US Dollar shopping cart (links on each product page) or we accept orders by email (usasales@everestbiotech.com), fax (888-841-9041), phone (888-320-4628). Please include the following information with your order:
In stock orders received by 13.30 PST on Monday through Thursday are shipped the same day. Orders are placed with and invoiced by our US partner Abcore LLC.
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Target Protein
Principal Names: embryonic liver differentiation factor 10, ATPase, H+ transporting, lysosomal interacting protein 2, XMRE, MSTP009, MRXE, MGC99577, HT028, ELDF10, ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9, vacuolar ATP synthase membrane sector associated protein M8-9, ATPase membrane sector associated protein M8-9, V-ATPase M8.9 subunit, renin receptor, ATP6M8-9, APT6M8-9, M8-9, ATPase, H+ transporting, lysosomal interacting protein 2, ATP6IP2, ATP6AP2Official Symbol: ATP6AP2
Accession Number(s): NP_005756.2
Human GeneID(s): 10159
Non-Human GeneID(s): 70495 (mouse)
Immunogen
Peptide with sequence C-SIIYRMTNQKIRMD, from the C Terminus of the protein sequence according to NP_005756.2.
Please note the peptide is available for sale.
Purification and Storage
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Tested
Peptide ELISA: antibody detection limit dilution 1:16000.Western blot: Approx 37kDa band observed in Human Kidney lysates (calculated MW of 39.0kDa according to NP_005756.2). Recommended for use at 0.25-1µg/ml
IHC: This antibody has been successfully used for human placenta in the following paper: Pringle et al, J Renin Angiotensin Aldosterone Syst. 2010 Aug 11, PMID: 20702505.
Species Reactivity
Tested: Human, Mouse, RatExpected from sequence similarity: Human, Mouse, Rat, Cow
Specific References
This antibody has been successfully used in the following papers:
Pringle KG, Zakar T, Yates D, Mitchell CM, Hirst JJ, Lumbers ER.
Molecular evidence of a (pro)renin/(pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2.
J Renin Angiotensin Aldosterone Syst. 2010 Aug 11.
PMID: 20702505
The goat polyclonal antibody used in the following papers was manufactured by us:
Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AH, Uddin MN, Nakagawa T, Nishiyama A, Suzuki F, Inagami T, Itoh H.
Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats.
J Am Soc Nephrol. 2007 Jun;18(6):1789-95.
PMID: 17494887
Advani A, Kelly DJ, Cox AJ, White KE, Advani SL, Thai K, Connelly KA, Yuen D, Trogadis J, Herzenberg AM, Kuliszewski MA, Leong-Poi H, Gilbert RE.
The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney.
Hypertension. 2009 Aug;54(2):261-9.
PMID: 19546380
Schefe JH, Neumann C, Goebel M, Danser J, Kirsch S, Gust R, Kintscher U, Unger T, Funke-Kaiser H.
Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren.
J Hypertens. 2008 Sep;26(9):1787-94.
PMID: 18698213