Change country

Voltage-gated Ion Channels

Voltage-gated ion channels are transmembrane ion channels that are activated by changes in electrical potential difference in the cell membrane. They have a crucial role in excitable neuronal and muscle tissues, allowing a rapid and co-ordinated depolarisation.

Voltage-gated sodium channels are responsible for the initial upstroke of the action potential. The SCN5A (Nav1.5) channel is primarily found in cardiac myocytes.

Voltage-dependent calcium channels (VDCC) are a group of voltage-gated ion channels found in excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the ion Ca2+. Activation of specific VDCCs allows Ca2+ ions to enter the cell, which results in muscles to muscular contraction , in neurons change of membrane potential and therefore neuronal excitability.

Voltage-gated potassium channels play a crucial role during action potential in returning the depolarized cell to a resting state. In excitable cells such as neurons , they shape action potentials and set the resting membrane potential . By contributing to the regulation of the action potential duration in cardiac muscle , malfunction of potassium channels may cause life-threatening arrhythmias and the KCNQ channels which can form heteromers, such as KCNQ2/3 and KCNQ3/5, may be responsible for BNFC (beneign neonatal familial convulsions).

Please view our antibodies against voltage gated ion channels below, search our website or view our polyclonal antibody production and custom antibody services.

 

Antibodies for Voltage-gated Ion Channels

Everest code Principal name Applications Tested Species reactivity Size available
EB07524 Goat Anti-AMPA1 / GLUR1 Antibody ELISA Human, Mouse, Rat, Dog 100µg/200µl
EB08821 Goat Anti-CACNA1C Antibody Pep-ELISA, WB Human 100µg/200µl
EB09647 Goat Anti-CACNA1G Antibody Pep-ELISA Human, Rat, Dog, Cow 100µg/200µl
EB07832 Goat Anti-CACNA2D1 Antibody Pep-ELISA, WB Human 100µg/200µl
EB06591 Goat Anti-CACNB4 (C terminus) Antibody Pep-ELISA, WB Human, Mouse, Rat, Pig 100µg/200µl
EB07531 Goat Anti-CACNB4 (internal) Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog 100µg/200µl
EB08583 Goat Anti-CLCA1 (aa872-884) Antibody Pep-ELISA, WB Human 100µg/200µl
EB06800 Goat Anti-CLCA1 Antibody Pep-ELISA, WB Human 100µg/200µl
EB07738 Goat Anti-CLIC4 Antibody Pep-ELISA, WB, IHC, IF Human, Mouse, Rat, Dog 100µg/200µl
EB09671 Goat Anti-Connexin 30 / GJB6 Antibody Pep-ELISA Human, Mouse, Rat, Cow 100µg/200µl
EB08036 Goat Anti-GIRK2 / KCNJ6 Antibody Pep-ELISA, WB Human, Mouse, Rat. This batch is not expected to cross-react with Rat and Mouse in Western blot. 100µg/200µl
EB07064 Goat Anti-ITPR3 Antibody Pep-ELISA Human, Mouse, Rat, Dog, Cow 100µg/200µl
EB07272 Goat Anti-KCNA2 Antibody ELISA Human, Mouse, Rat, Dog 100µg/200µl
EB08061 Goat Anti-KCNB1 / DRK1 Antibody Pep-ELISA Human, Mouse, Dog, Cow, Pig 100µg/200µl
EB07388 Goat Anti-KCNC3 Antibody Pep-ELISA, WB Human 100µg/200µl
EB07765 Goat Anti-KCNJ11 / KATP / Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB07766 Goat Anti-Kcnj11 / Kir6.2 Antibody Pep-ELISA, WB, IHC Human, Mouse, Rat, Dog 100µg/200µl
EB09130 Goat Anti-KCNJ1 / ROMK Antibody Pep-ELISA, WB Human 100µg/200µl
EB08857 Goat Anti-KCNMA1 Antibody Pep-ELISA Human, Mouse, Rat, Cow 100µg/200µl
EB09214 Goat Anti-KCNQ1 Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog, Cow 100µg/200µl
EB09213 Goat Anti-KCNQ3 Antibody Pep-ELISA Human, Mouse, Rat, Pig 100µg/200µl
EB08068 Goat Anti-KCNQ4 Antibody Pep-ELISA, WB Human 100µg/200µl
EB09212 Goat Anti-KCNQ5 Antibody Pep-ELISA Human, Mouse, Rat, Pig, Dog 100µg/200µl
EB07341 Goat Anti-NMDA receptor 1 / GRIN1 Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog. This batch is not expected to cross-react with Mouse in Western blot. 100µg/200µl
EB09022 Goat Anti-ORAI1 / CRACM1 Antibody Pep-ELISA, WB Human, Dog, Pig 100µg/200µl
EB09509 Goat Anti-P2RX7 / P2X7 receptor Antibody Pep-ELISA, WB, IHC Human, Mouse, Rat, Dog 100µg/200µl
EB08830 Goat Anti-P2X4 / P2X4R Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog, Cow 100µg/200µl
EB06912 Goat Anti-SCN5A Antibody Pep-ELISA Human, Mouse, Rat, Dog, Cow 100µg/200µl
EB08972 Goat Anti-SCNN1G Antibody Pep-ELISA Human 100µg/200µl
EB07328 Goat Anti-Serotonin receptor 3A / HTR3A Antibody Pep-ELISA, WB, ICC, IF Human 100µg/200µl
EB09495 Goat Anti-Serotonin Receptor 3B / HTR3B Antibody Pep-ELISA, WB Human 100µg/200µl
EB09610 Goat Anti-TPCN2 Antibody Pep-ELISA Human 100µg/200µl
EB08033 Goat Anti-Transmembrane protein 37 Antibody Pep-ELISA Human 100µg/200µl
EB08796 Goat Anti-TRPC4 Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog, Pig, Cow 100µg/200µl
EB09128 Goat Anti-TRPC4AP Antibody Pep-ELISA, WB Human 100µg/200µl
EB06901 Goat Anti-TRPC6 Antibody Pep-ELISA, FC Human, Dog, Pig, Cow 100µg/200µl
EB08831 Goat Anti-TRPC6 (C-term) Antibody Pep-ELISA, WB Human, Cow 100µg/200µl
EB09257 Goat Anti-TRPC7 Antibody Pep-ELISA, WB, IP Human, Mouse, Rat, Dog 100µg/200µl
EB09256 Goat Anti-TRPM5 / MTR1 Antibody Pep-ELISA, WB Human, Mouse, Rat 100µg/200µl
EB05129 Goat Anti-TRPM7 / LTRPC7 Antibody Pep-ELISA, IHC Human, Mouse, Rat, Dog, Pig 100µg/200µl
EB08366 Goat Anti-TRPM8 Antibody Pep-ELISA Human, Mouse, Rat 100µg/200µl
EB08811 Goat Anti-TRPV2 Antibody Pep-ELISA Human 100µg/200µl
EB08812 Goat Anti-Trpv2 (mouse) Antibody Pep-ELISA, WB Mouse, Rat 100µg/200µl
EB07235 Goat Anti-TRPV3 (aa607-618) Antibody ELISA Human, Dog 100µg/200µl
EB08468 Goat Anti-TRPV3 (aa610-622) Antibody ELISA Human 100µg/200µl
EB08799 Goat Anti-TRPV3 (aa762-773) Antibody Pep-ELISA, WB-Trf Human, Mouse, Rat, Dog 100µg/200µl
EB08515 Goat Anti-TRPV5 Antibody Pep-ELISA, WB, ICC, IF Human, Mouse, Rat, Dog, Pig, Cow 100µg/200µl
EB06324 Goat Anti-VDAC2 (C Terminus) Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog, Pig, Cow 100µg/200µl
EB07409 Goat Anti-VDAC2 (Internal) Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog 100µg/200µl