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Goat Anti-KCNQ3 Antibody (EB09213)
| Code | Name | Applications | Availability | Size | Species reactivity | Price | Grade | |
|---|---|---|---|---|---|---|---|---|
| EB09213 | Goat Anti-KCNQ3 Antibody | ELISA |  |
100µg specific antibody in 200µl | Human, Mouse, Rat, Pig | $195.00 |  |
|
Ordering Information forOrder direct from Everest
$35.00: Overnight shipping to United States of America
Sent via overnight courier arrives approximately next day to mainland USA. Order offlineNow shipping direct to US customers! All orders will be shipped to you by our logistics partner in Kentucky. Almost all products are held in stock for immediate shipment, see individual product pages for availability. Orders are placed with and invoiced by Everest Biotech Ltd in the United Kingdom. Please order through the US Dollar shopping cart (links on each product page) or we accept orders by email (sales@everestbiotech.com), fax (888-841-9041), phone (888-320-GOAT) or mail. Please include the following information with your order:
In stock orders received by 09.30 PST / 12.30 EST on Monday through Thursday are shipped the same day. OR
Order from our local distributorAxxora, LLC6181 Cornerstone Court East Suite 103, Tel: 858-550-8830 |
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Target Protein
Principal Names: potassium voltage-gated channel KQT-like protein 3, potassium channel, voltage-gated, subfamily Q, member 3, KV7.3, EBN2, BFNC2, potassium voltage-gated channel, KQT-like subfamily, member 3, KCNQ3Official Symbol: KCNQ3
Accession Number(s): NP_004510.1
Human GeneID(s): 3786
Non-Human GeneID(s): 110862 (mouse), 29682 (rat)
Immunogen
Peptide with sequence C-SDSVWTPSNKPI, from the C-Terminus of the protein sequence according to NP_004510.1.
Please note the peptide is available for sale.
Purification and Storage
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Tested
Peptide ELISA: antibody detection limit dilution 1:16000.Western blot: Preliminary experiments gave an approx. 23kDa band in Human Brain (Cerebral Cortex, Amygdala, Hippocampus) lysates after 0.3µg/ml antibody staining. Please note that currently we can not find an explanation in the literature for the band we observe given the calculated size of 96.7kDa according to NP_004510.1. The 23kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Species Reactivity
Tested:Expected from sequence similarity: Human, Mouse, Rat, Pig
Background Reference
Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ.
Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2.
J Biol Chem. 2007 Apr 20;282(16):12135-42.
PMID: 17322297