Goat Anti-LAMC2 Antibody

100 µg

ladsin (140kDa)|epiligrin|cell-scattering factor (140kDa)|MGC141938|MGC138491|nicein-100kDa|nicein (100kDa)|laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)|kalinin-105kDa|kalinin (105kD)|BM600-100kDa|LAMNB2|LAMB2T|EBR2A|EBR2|BM600|B2T|HGNC:6493|laminin, gamma 2|LAMC2

NP_005553.2; NP_061486.2

EBP07078

Peptide with sequence C-QKVDTRAKNAGVTIQD, from the internal region of the protein sequence according to NP_005553.2; NP_061486.2.

This antibody is expected to recognise both reported isoforms (NP_005553.2; NP_061486.2)

C-QKVDTRAKNAGVTIQD

Refrigerated

Human

3918

Antibody detection limit dilution 1:16000.

Preliminary experiments gave bands at approx 170kDa and 55-60kDa in Human Lung lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 131kDa according to NP_005553.1 and 122kDa according to NP_061486.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Pep-ELISA