Goat Anti-PGRMC1 / MPR Antibody

$464.00

SKU Unit Size Price

Select a unit size:


SKU: EB07207
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
progesterone binding protein|HPR6.6|HGNC:16090|progesterone receptor membrane component 1|MPR|PGRMC1
Usage Summary
Immunofluorescence: This antibody has been successfully used in IF on Human: Izzo, N. J et al. (2014) PMID: 25390692.
Accession ID
NP_006658.1
Blocking Peptide
EBP07207
Immunogen
Peptide with sequence C-EPKDESARKND, from the C Terminus of the protein sequence according to NP_006658.1.
Peptide Sequence
C-EPKDESARKND
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human, Mouse, Rat
Reactive Species
Human, Mouse
Human Gene ID
10857
Mouse Gene ID
53328
Product Grade
IHC Results
Paraffin embedded Human Testis. Recommended concentration: 5µg/ml.
ELISA Detection Limit
Antibody detection limit dilution 1:4000.
Western Blot
Approx 24kDa band observed in Human Kidney, Liver and Testis lysates, and approx 25kDa in Mouse Testis lysates (calculated MW of 21.7kDa according to Human NP_006658.1 and Mouse NP_058063.2). These molecular weights are routinely observed by other sources. Recommended concentration: 0.1-0.3µg/ml. Primary incubation 1 hour at room temperature.
Application Type
Pep-ELISA, WB, IHC, IF
Selected References
[{"pmid": 25390692, "intro": "This antibody has been successfully used in IF on Human:", "title": "Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity.", "author": "Izzo, N. J., Xu, J., et al.", "journal": "PLoS One. 2014 Nov 12;9(11):e111899."}]