Goat Anti-ABCC4 / MRP4 Antibody

$423.00

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SKU: EB06538
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
multidrug resistance-associated protein 4; multispecific organic anion transporter B|canalicular multispecific organic anion transporter (ABC superfamily)|bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)|ATP-binding cassette, sub-family C, member 4|RP11-74A12.1|Multidrug Resistance Protein 4|canalicular multispecific organic anion transporter (ABC superfamily)|ATP-binding cassette, sub-family C (CFTR/MRP), member 4|EST170205|MOAT-B|MOATB|MRP4|ABCC4
Accession ID
NP_005836.2
Blocking Peptide
EBP06538
Immunogen
Peptide with sequence CNGQPSTLTIFETAL, from the C Terminus of the protein sequence according to NP_005836.2.
Product Comments
This antibody is expected to recognize isoform 1 (NP_005836.2) only.
Peptide Sequence
CNGQPSTLTIFETAL
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human, Mouse, Rat
Reactive Species
Human
Human Gene ID
10257
Rat Gene ID
170924
Product Grade
IHC Results
In paraffin embedded Human Prostate shows membranous staining in the secretory cells. Recommended concentration, 4-6µg/ml.
ELISA Detection Limit
Antibody detection limit dilution 1:32000.
Application Type
Pep-ELISA, IHC
Selected References
[{"pmid": 20395535, "intro": "This antibody (previous batch) has been successfully used in ICC/IF on Human:", "title": "Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression.", "author": "Xu S, Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL.", "journal": "Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G126-35."}, {"pmid": 23503867, "intro": "This antibody (previous batch) has been successfully used in IHC on Human:", "title": "Multidrug\r\nresistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression.", "author": "Montani M, Herrmanns T, Müntener M, Wild P, Sulser T, Kristiansen G", "journal": "Virchows Arch. 2013 Apr;462(4):437-43."}, {"pmid": 23978715, "intro": "This antibody (previous batch) has been successfully used in WB on Human:", "title": "Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice.", "author": "Weerachayaphorn J, Luo Y, Mennone A, Soroka CJ, Harry K, Boyer JL", "journal": "J Hepatol. 2014 Jan;60(1):160-6"}, {"pmid": 23472950, "intro": "This antibody (previous batch) has been successfully used in IHC on Human:", "title": "Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A4.", "author": "Gori I, Rodriguez Y, Pellegrini C, Achtari C, Hornung D, Chardonnens E, Wunder D, Fiche M, Canny GO.", "journal": "Fertil Steril. 2013 Mar 6."}, {"pmid": 22345550, "intro": "This antibody (previous batch) has been successfully used in WB on Mouse:", "title": "Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.", "author": "Weerachayaphorn J, Mennone A, Soroka CJ, Harry K, Hagey LR, Kensler TW, Boyer JL.", "journal": "Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G925-36."}]