Goat Anti-ADAM17 / TACE Antibody

$423.00

Category: Primary Antibodies
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SKU: EB05382
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
tumor necrosis factor, alpha, converting enzyme|snake venom-like protease|ADAM metallopeptidase domain 18|CD156B|ADAM18|ADAM metallopeptidase domain 17|snake venom-like protease|a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)|a disintegrin and metalloproteinase domain 17|TNF-alpha converting enzyme|cSVPADAM metallopeptidase domain 17|TACE|MGC71942|CD156b|CD156b|cSVP|CSVP|a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)|TACE|ADAM17
Accession ID
NP_003174.3
Blocking Peptide
EBP05382
Immunogen
Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3.
Product Comments
This antibody is expected to recognise isoform 1 (represented by NP_003174.3) and not isoform 2 (represented by NP_068604).
Peptide Sequence
LQRQNRVDSKETEC
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human, Mouse, Rat
Reactive Species
Human
Human Gene ID
6868
Mouse Gene ID
11491
Product Grade
ELISA Detection Limit
Antibody detection limit dilution 1:32000.
Western Blot
Approx 125-130kDa band observed in Hela, Jurkat and U937 lysates (predicted MW of kDa according to NP_003174.3 but glycosylated). Recommended for use at 0.1-1µg/ml. Primary incubation was for 1 hour. The observed molecular weights correspond to earlier findings in literature with different antibodies (Le Gall et al, J Cell Sci. 2010 Nov 15;123(Pt22):3913-22; PMID: 20980382)
Application Type
Pep-ELISA, WB

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