Goat Anti-ADRB1 Antibody

$423.00

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SKU: EB07133
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
beta-1-adrenergic receptor|RHR|BETA1AR|B1AR|ADRB1R|adrenergic, beta-1-, receptor|ADRB1
Accession ID
NP_000675.1
Blocking Peptide
EBP07133
Immunogen
Peptide with sequence ESDEARRCYNDPK, from the internal region of the protein sequence according to NP_000675.1.
Peptide Sequence
ESDEARRCYNDPK
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human, Mouse, Rat, Dog
Reactive Species
Human
Human Gene ID
153
Product Grade
IHC Results
Paraffin embedded Human Heart. Recommended concentration: 4µg/ml.
ELISA Detection Limit
Antibody detection limit dilution 1:4000.
Western Blot
This antibody is not recommended for use in Western blotting.
Application Type
Pep-ELISA, IHC
Selected References
[{"pmid": 29425252, "intro": "This antibody (previous batch) has been successfully used in the following paper:", "title": "Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology.", "author": "Wenzel K, Schulze-Rothe S, Müller J, Wallukat G, Haberland A.", "journal": "PLoS One. 2018 Feb 9;13(2):e0192615"}, {"pmid": 28795160, "intro": "This antibody (previous batch) has been successfully used in the following paper:", "title": "Performance and in-house validation of a bioassay for the determination of beta1-auto antibodies found in patients with cardiomyopathy.", "author": "Wenzel K, Schulze-Rothe S, Haberland A, Müller J, Wallukat G, Davideit H", "journal": "Heliyon. 2017 Jul 31;3(7): e00362."}, {"pmid": 22850243, "intro": "This antibody (previous batch) has been successfully used for In Vitro Testing of Apheresis Column Functionality in Rat:", "title": "The first aptamer-apheresis column specifically for clearing blood of ?1-receptor autoantibodies.", "author": "Wallukat G, Haberland A, Berg S, Schulz A, Freyse EJ, Dahmen C, Kage A, Dandel M, Vetter R, Salzsieder E, Kreutz R, Schimke I.", "journal": "Circ J. 2012;76(10):2449-55."}, {"pmid": 27375076, "intro": "This antibody (previous batch) has been successfully used in the following paper:", "title": "Aptamer BC 007 - A broad spectrum neutralizer of pathogenic autoantibodies against G-protein-coupled receptors", "author": "Annekathrin Haberland, Martin Holtzhauer, Alice Schlichtiger, Sabine Bartel, Ingolf Schimke, Johannes Müller, Michael Dandel, Peter B Luppa, Gerd Wallukat", "journal": "Eur J Pharmacol. 2016 Oct 15:789:37-45."}, {"pmid": 21868696, "intro": "This antibody (previous batch) has been successfully used in IP on DNA aptamers in vitro:", "title": "Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies.", "author": "Haberland A, Wallukat G, Dahmen C, Kage A, Schimke I.", "journal": "Circ Res. 2011 Oct 14;109(9):986-92."}, {"pmid": 20117461, "intro": "This antibody (previous batch) has been successfully used in Assay Standardization (beating frequency) of Rat Cardiomyocytes:", "title": "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients.", "author": "Wallukat G, Muñoz Saravia SG, Haberland A, Bartel S, Araujo R, Valda G, Duchen D, Diaz Ramirez I, Borges AC, Schimke I.", "journal": "J Am Coll Cardiol. 2010 Feb 2;55(5):463-8."}, {"pmid": 29538413, "intro": "This antibody (previous batch) has been successfully used in Assay Standardization of Rat Cardiomyocytes:", "title": "Functional autoantibodies in patients with different forms of dementia", "author": "Gerd Wallukat , Harald Pruss, Johannes Muller , Ingolf Schimke", "journal": "PLoS One. 2018 Mar 14;13(3):e0192778."}, {"pmid": 37474759, "intro": "This antibody (previous batch) has been successfully used in the following paper:", "title": "Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools.", "author": "Ting-Yu Lin, Quynh N Mai, Hao Zhang, Emily Wilson, Huan-Chieh Chien, Sook Wah Yee, Kathleen M Giacomini, Jeffrey E Olgin, Roshanak Irannejad", "journal": "Nat Chem Biol. 2023 Jul 20."}]