Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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Unit Size 100 µg | |
Storage Instructions Aliquot and store at -20°C. Minimize freezing and thawing. | |
Synonym / Alias Names autoimmune regulator AIRE|autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy)|autoimmune regulator (APECED protein)|PGA1|APSI|APS1|APECED|AIRE1|autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)|AIRE | |
Accession ID NP_000374.1 | |
Blocking Peptide EBP07267 | |
Immunogen Peptide with sequence C-KDVDLSQPRKGRKP, from the internal region of the protein sequence according to NP_000374.1. | |
Peptide Sequence C-KDVDLSQPRKGRKP | |
Purification Method Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. | |
Shipping Instructions Refrigerated | |
Predicted Species Human, Rat, Dog, Cow | |
Reactive Species Human, Pig | |
Human Gene ID 326 | |
Product Grade  | |
IHC Results In paraffin embedded Human Thymus shows nuclear staining in select thymocytes. This antibody has been successfully used in IHC on Human: Ströbel P et al. (2014) PMID: 24236644. This antibody has been successfully used in IHC on Pig: Suzuki S et al. (2014) PMID: 24770647. | |
ELISA Detection Limit Antibody detection limit dilution 1:32000. | |
Western Blot Appr. 60kDa in transfected HEK293 lysates (calculated MW of 57.7kDa according to NP_000374.1). Recommended concentration: 0.5-1.0 µg/ml. | |
Application Type Pep-ELISA, WB, IHC |
Goat Anti-AIRE Antibody
$423.00
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Selected References [{"pmid": 24770647, "intro": "This antibody has been successfully used in IHC on Pig:", "title": "Transcriptional and histological analyses of the thymic developmental process in the fetal pig.", "author": "Suzuki S, Suzuki M, Nakai M, Sembon S, Fuchimoto D, Onishi A.", "journal": "Exp Anim. 2014;63(2):215-25."}, {"pmid": 24236644, "intro": "This antibody has been successfully used in IHC on Human:", "title": "Corticomedullary differentiation and maturational\r\narrest in thymomas.", "author": "Ströbel P, Hartmann E, Rosenwald A, Kalla J, Ott G, Friedel G, Schalke B, Kasahara M, Tomaru U, Marx A.", "journal": "Histopathology. 2014 Mar;64(4):557-66."}] |