Goat Anti-CYLD (C terminus) Antibody

$255.00

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SKU: EB06401
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
CYLD|EAC|CDMT|CYLD1|CYLDI|FLJ31664|FLJ78684|HSPC057|KIAA0849|USPL2|deubiquitinating enzyme CYLD|ubiquitin carboxyl-terminal hydrolase CYLD|ubiquitin specific peptidase like 2|ubiquitin thiolesterase CYLD|ubiquitin-specific-processing protease CYLD|cylindromatosis (turban tumor syndrome)|MFT|MFT1|SBS|TEM
Accession ID
NP_056062.1; NP_001035814.1; NP_001035877.1
Immunogen
Peptide with sequence CMYQSPTMSLYK, from the C Terminus of the protein sequence according to NP_056062.1; NP_001035814.1; NP_001035877.1.
Product Comments
This antibody is expected to recognize both reported isoforms (NP_056062.1 and NP_001035814.1; NP_001035877.1).
Peptide Sequence
CMYQSPTMSLYK
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human, Mouse, Rat, Dog, Cow
Human Gene ID
1540
Product Grade
ELISA Detection Limit
Antibody detection limit dilution 1:16000.
Western Blot
Preliminary experiments gave no signal but low background in human kidney and Hela lysates at up to 1µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Application Type
ELISA
Selected References
[{"pmid": 14676304, "intro": "", "title": "The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor.", "author": "Regamey A, Hohl D, Liu JW, Roger T, Kogerman P, Toftgard R, Huber M. ", "journal": "J Exp Med. 2003 Dec 15;198(12):1959-64. "}]