Goat Anti-DYRK1A Antibody

$423.00

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SKU: EB11483
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
serine/threonine-specific protein kinase|serine/threonine kinase MNB|protein kinase minibrain homolog|OTTHUMP00000174799|OTTHUMP00000109094|OTTHUMP00000109091|OTTHUMP00000109090|MRD7|MNBH|MNB/DYRK protein kinase|mnb protein kinase homolog hp86|MNB|HP86|hMNB|DYRK1A|DYRK1|DYRK|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A|dual specificity YAK1-related kinase|dual specificity tyrosine-phosphorylation-regulated kinase 1A
Usage Summary
Immunoprecipitation: This product has been successfully used in IP on Human: Widowati et al, BMC Res Notes. 2018 May 15;11(1):297. PMID: 29764512.
Accession ID
NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1
Blocking Peptide
EBP11483
Immunogen
Peptide with sequence PHSHQYSDRRQPN-C, from the N Terminus of the protein sequence according to NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1.
Product Comments
This antibody is expected to recognize all reported isoforms (NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1). This antibody is not expected to cross-react with DYRK1B.
Peptide Sequence
PHSHQYSDRRQPN-C
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human, Mouse, Rat, Dog, Pig, Cow
Reactive Species
Human
Human Gene ID
1859
Mouse Gene ID
13548
Rat Gene ID
25255
Product Grade
ELISA Detection Limit
Antibody detection limit dilution 1:64000.
Western Blot
Approx 80kDa band observed in lysates of cell line K562 (calculated MW of 85.6kDa according to NP_001387.2). Recommended concentration: 0.5-2µg/ml. Primary incubation was 1 hour.
Application Type
Pep-ELISA, WB, IP
Selected References
[{"pmid": 29764512, "intro": "This antibody has been successfully used in IP on Human:", "title": "Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A", "author": "Esti Wahyu Widowati, Simone Bamberg-Lemper and Walter Becky", "journal": "BMC Res Notes. 2018 May 15;11(1):297. "}]