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Goat Anti-FOXC1 (C Term) Antibody (EB06006)
| Code | Name | Applications | Availability | Size | Species reactivity | Price | Grade | |
|---|---|---|---|---|---|---|---|---|
| EB06006 | Goat Anti-FOXC1 (C Term) Antibody | Pep-ELISA, WB, IHC, ChIP |  |
100µg specific antibody in 200µl | Human, Mouse | $315.00 |  |
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Ordering Information forOrder direct from Everest
$40.00: Overnight shipping to United States of America
Sent via overnight courier arrives approximately next day to mainland USA. Please note that your order will be processed and invoiced by our US partner Abcore LLC. Order offlineNow shipping direct to US customers! 99% of products are held in stock for immediate shipment, see individual product pages for availability. Please order through the US Dollar shopping cart (links on each product page) or we accept orders by email (usasales@everestbiotech.com), fax (888-841-9041), phone (888-320-4628). Please include the following information with your order:
In stock orders received by 13.30 PST on Monday through Thursday are shipped the same day. Orders are placed with and invoiced by our US partner Abcore LLC.
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Target Protein
Principal Names: myeloid factor-delta, forkhead/winged helix-like transcription factor 7, RIEG3, FREAC-3, Forkhead, drosophila, homolog-like 7, forkhead-related activator 3, forkhead (Drosophila)-like 7, iridogoniodysgenesis type 1, FREAC3, IRID1, FKHL7, IHG1, IGDA, ARA, forkhead box C1, FOXC1Official Symbol: FOXC1
Accession Number(s): NP_001444.2
Human GeneID(s): 2296
Non-Human GeneID(s): 17300 (mouse)
Immunogen
Peptide with sequence RTSGAFVYDCSKF, from the C Terminus of the protein sequence according to NP_001444.2.
Please note the peptide is available for sale.
Purification and Storage
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Tested
Peptide ELISA: antibody detection limit dilution 1:32000.Western blot: Approx 55kDa band observed in Human Bone Marrow lysates (calculated MW of 56.8kDa according to NP_001444.1). Recommended concentration: 0.5-1.5µg/ml.
IHC: In paraffin embedded Human Kidney shows nuclear staining of some cells in the glomeruli and in paraffin embedded Human Spleen shows nucleolar staining in many splenocytes. Recommended concentration, 3-5 µg/ml. Customer successfully used in IHC-P in mouse (periocular mesenchyme, cornea)
Chromatin immunoprecipitation: Customer successfully used this antibody in ChIP from human cell line.
Species Reactivity
Tested: Human, MouseExpected from sequence similarity: Human, Mouse
Specific References
The goat polyclonal antibody used in this paper was manufactured by us:
Hayashi H, Kume T.
Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells.
PLoS One. 2008 Jun 11;3(6):e2401.
PMID: 18545664
The goat polyclonal antibody used in this paper was manufactured by us:
Berry FB, Skarie JM, Mirzayans F, Fortin Y, Hudson TJ, Raymond V, Link BA, Walter MA.
FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A.
Hum Mol Genet. 2008 Feb 15;17(4):490-505.
PMID: 17993506
The goat polyclonal antibody used in this paper was manufactured by us:
Tamimi Y, Skarie JM, Footz T, Berry FB, Link BA, Walter MA.
FGF19 is a target for FOXC1 regulation in ciliary body-derived cells.
um Mol Genet. 2006 Nov 1;15(21):3229-40.
PMID: 17000708
The goat polyclonal antibody used in this paper was manufactured by us:
Berry FB, Lines MA, Oas JM, Footz T, Underhill DA, Gage PJ, Walter MA.
Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis.
Hum Mol Genet. 2006 Mar 15;15(6):905-19.
PMID: 16449236