Goat Anti-p15INK4b (isoform 2) Antibody

$423.00

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SKU: EB11215
Formulation
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Unit Size
100 µg
Storage Instructions
Aliquot and store at -20°C. Minimize freezing and thawing.
Synonym / Alias Names
CDKN2B| TP15| p15-INK4b| p15INK4b| p15_INK4B| p15 CDK inhibitor| P15| p14-INK4b| p14_INK4B| p14_CDK inhibitor| multiple tumor suppressor 2| MTS-2| MTS2| INK4B| cyclin-dependent kinases 4 and 6 binding protein| cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)| cyclin-dependent kinase 4 inhibitor B| CDK4I| CDK4B inhibitor| CDK inhibitory protein
Accession ID
NP_004927.2; NP_511042.1
Blocking Peptide
EBP11215
Immunogen
Peptide with sequence C-RQGARERGARP, from the C Terminus of the protein sequence according to NP_004927.2; NP_511042.1.
Product Comments
This antibody is expected to recognize isoform 2 (NP_511042.1) only.
Peptide Sequence
C-RQGARERGARP
Purification Method
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Shipping Instructions
Refrigerated
Predicted Species
Human
Reactive Species
Human
Human Gene ID
1030
Product Grade
ELISA Detection Limit
Antibody detection limit dilution 1:128000.
Western Blot
Approx 12+14kDa bands observed in Human Gastrointestinal cancer lysates (calculated MW of 8.1kDa according to NP_511042.1). The observed 14kDa cannot represent isoform 1 and therefore it most likely represents another posttranslational modification of isoform 2. Recommended concentration: 1-3µg/ml.
Application Type
Pep-ELISA, WB