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Voltage-gated ion channels are transmembrane ion channels that are activated by changes in electrical potential difference in the cell membrane. They have a crucial role in excitable neuronal and muscle tissues, allowing a rapid and co-ordinated depolarisation.
Voltage-gated sodium channels are responsible for the initial upstroke of the action potential. The SCN5A (Nav1.5) channel is primarily found in cardiac myocytes.
Voltage-dependent calcium channels (VDCC) are a group of voltage-gated ion channels found in excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the ion Ca2+. Activation of specific VDCCs allows Ca2+ ions to enter the cell, which results in muscles to muscular contraction , in neurons change of membrane potential and therefore neuronal excitability.
Voltage-gated potassium channels play a crucial role during action potential in returning the depolarized cell to a resting state. In excitable cells such as neurons , they shape action potentials and set the resting membrane potential . By contributing to the regulation of the action potential duration in cardiac muscle , malfunction of potassium channels may cause life-threatening arrhythmias and the KCNQ channels which can form heteromers, such as KCNQ2/3 and KCNQ3/5, may be responsible for BNFC (beneign neonatal familial convulsions).
Please view our antibodies against voltage gated ion channels below, search our website or view our polyclonal antibody production and custom antibody services.
Everest code | Principal name | Applications Tested | Species reactivity | Size available |
---|---|---|---|---|
EB07524 | Goat Anti-AMPA1 / GLUR1 Antibody | Pep-ELISA | Human, Mouse, Rat, Dog | 100µg/200µl |
EB08821 | Goat Anti-CACNA1C Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB09647 | Goat Anti-CACNA1G Antibody | Pep-ELISA | Human, Rat, Dog, Cow | 100µg/200µl |
EB07832 | Goat Anti-CACNA2D1 Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB06591 | Goat Anti-CACNB4 (C terminus) Antibody | Pep-ELISA, WB | Human, Cow | 100µg/200µl |
EB07531 | Goat Anti-CACNB4 (internal) Antibody | Pep-ELISA, WB | Human, Mouse, Rat, Dog | 100µg/200µl |
EB08583 | Goat Anti-CLCA1 (aa872-884) Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB06800 | Goat Anti-CLCA1 Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB07738 | Goat Anti-CLIC4 Antibody | Pep-ELISA, WB, IHC, IF | Human, Mouse, Rat, Dog | 100µg/200µl |
EB09671 | Goat Anti-Connexin 30 / GJB6 Antibody | Pep-ELISA | Human, Mouse, Rat, Cow | 100µg/200µl |
EB08036 | Goat Anti-GIRK2 / KCNJ6 Antibody | Pep-ELISA, WB, ICC | Human, Mouse, Rat | 100µg/200µl |
EB07064 | Goat Anti-ITPR3 Antibody | Pep-ELISA | Human, Mouse, Rat, Dog, Cow | 100µg/200µl |
EB07272 | Goat Anti-KCNA2 Antibody | Pep-ELISA | Human, Mouse, Rat, Dog | 100µg/200µl |
EB08061 | Goat Anti-KCNB1 / DRK1 Antibody | Pep-ELISA | Human, Mouse, Dog, Cow, Pig | 100µg/200µl |
EB07388 | Goat Anti-KCNC3 Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB07765 | Goat Anti-KCNJ11 / KATP / Antibody | Pep-ELISA, WB, IHC | Human | 100µg/200µl |
EB07766 | Goat Anti-Kcnj11 / Kir6.2 Antibody | Pep-ELISA, WB, IHC | Human, Mouse, Rat, Dog | 100µg/200µl |
EB09130 | Goat Anti-KCNJ1 / ROMK Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB08857 | Goat Anti-KCNMA1 Antibody | Pep-ELISA | Human, Mouse, Rat, Cow | 100µg/200µl |
EB09214 | Goat Anti-KCNQ1 Antibody | Pep-ELISA, WB, IHC | Human, Mouse, Rat, Dog, Cow | 100µg/200µl |
EB09213 | Goat Anti-KCNQ3 Antibody | Pep-ELISA | Human, Mouse, Rat, Pig | 100µg/200µl |
EB08068 | Goat Anti-KCNQ4 Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB09212 | Goat Anti-KCNQ5 Antibody | Pep-ELISA | Human, Mouse, Rat, Pig, Dog | 100µg/200µl |
EB07341 | Goat Anti-NMDA receptor 1 / GRIN1 Antibody | Pep-ELISA, IF | Human, Mouse, Rat, Dog | 100µg/200µl |
EB09022 | Goat Anti-ORAI1 / CRACM1 Antibody | Pep-ELISA, WB | Human, Dog, Pig | 100µg/200µl |
EB09509 | Goat Anti-P2RX7 / P2X7 receptor Antibody | Pep-ELISA, WB, IHC, IF, FC | Human, Mouse, Rat, Dog | 100µg/200µl |
EB08830 | Goat Anti-P2X4 / P2X4R Antibody | Pep-ELISA, WB, FC | Human, Mouse, Rat, Dog, Cow | 100µg/200µl |
EB06912 | Goat Anti-SCN5A Antibody | Pep-ELISA, IHC | Human, Mouse, Rat, Dog, Cow | 100µg/200µl |
EB08972 | Goat Anti-SCNN1G Antibody | Pep-ELISA, IHC | Human | 100µg/200µl |
EB07328 | Goat Anti-Serotonin receptor 3A / HTR3A Antibody | Pep-ELISA, FC, IHC, ICC | Human | 100µg/200µl |
EB09495 | Goat Anti-Serotonin Receptor 3B / HTR3B Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB09610 | Goat Anti-TPCN2 Antibody | Pep-ELISA, IHC | Human | 100µg/200µl |
EB08033 | Goat Anti-Transmembrane protein 37 Antibody | Pep-ELISA | Human | 100µg/200µl |
EB08796 | Goat Anti-TRPC4 Antibody | Pep-ELISA, WB, IHC | Human, Mouse, Rat, Dog, Pig, Cow | 100µg/200µl |
EB09128 | Goat Anti-TRPC4AP Antibody | Pep-ELISA, WB | Human | 100µg/200µl |
EB06901 | Goat Anti-TRPC6 Antibody | Pep-ELISA, WB, FC | Human, Dog, Pig, Cow | 100µg/200µl |
EB08831 | Goat Anti-TRPC6 (C-term) Antibody | Pep-ELISA, WB | Human, Cow | 100µg/200µl |
EB09257 | Goat Anti-TRPC7 Antibody | Pep-ELISA, WB, IP | Human, Mouse, Rat, Dog, Cow | 100µg/200µl |
EB09256 | Goat Anti-TRPM5 / MTR1 Antibody | Pep-ELISA, WB | Human, Mouse, Rat | 100µg/200µl |
EB05129 | Goat Anti-TRPM7 / LTRPC7 Antibody | Pep-ELISA, IHC, IF | Human, Mouse, Rat, Dog, Pig | 100µg/200µl |
EB08366 | Goat Anti-TRPM8 Antibody | Pep-ELISA | Human, Mouse, Rat | 100µg/200µl |
EB08811 | Goat Anti-TRPV2 Antibody | Pep-ELISA | Human | 100µg/200µl |
EB08812 | Goat Anti-Trpv2 (mouse) Antibody | Pep-ELISA, IF | Mouse, Rat | 100µg/200µl |
EB07235 | Goat Anti-TRPV3 (aa607-618) Antibody | Pep-ELISA | Human, Mouse, Rat, Dog, Pig | 100µg/200µl |
EB08468 | Goat Anti-TRPV3 (aa610-622) Antibody | Pep-ELISA | Human | 100µg/200µl |
EB08799 | Goat Anti-TRPV3 (aa762-773) Antibody | Pep-ELISA, WB-Trf | Human, Mouse, Rat, Dog | 100µg/200µl |
EB08515 | Goat Anti-TRPV5 Antibody | Pep-ELISA, WB, ICC, IF | Human, Mouse, Rat, Dog, Pig, Cow | 100µg/200µl |
EB06324 | Goat Anti-VDAC2 (C Terminus) Antibody | Pep-ELISA, WB, IHC | Human, Mouse, Rat, Dog, Pig, Cow | 100µg/200µl |
EB07409 | Goat Anti-VDAC2 (Internal) Antibody | Pep-ELISA, WB | Human, Mouse, Rat, Dog | 100µg/200µl |