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Code | Name | Applications | Availability | Size | Tested species | Price | Grade | |
---|---|---|---|---|---|---|---|---|
EB06550 | Goat Anti-LRRK2 / PARK8 (near C Terminus) Antibody | Pep-ELISA, IF | 100µg specific antibody in 200µl | Human | $411.00 | |||
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Peptide with sequence CELAEKMRRTSV, from the internal region (near the C Terminus) of the protein sequence according to NP_940980.3.
Please note the peptide is available for sale.
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.
Immunofluorescence: Strong expression of the protein seen in the vesicles of A431 cells and in the vesicles and nuclei of A549 cells. Recommended concentration: 10µg/ml.
This antibody has been successfully used in the following paper:
Adrien De Guilhem De Lataillade, Martial Caillaud, Thibauld Oullier, Philippe Naveilhan, Carolina Pellegrini, Eduardo Tolosa, Michel Neunlist, Malvyne Rolli-Derkinderen, Ellen Gelpi, Pascal Derkinderen
LRRK2 expression in normal and pathologic human gut and in rodent enteric neural cell lines.
J Neurochem. 2023 Jan;164(2):193-209.
PMID: 36219522
This antibody (previous batch) has been successfully used in ICC on Human:
Sharma S, Bandopadhyay R, Lashley T, Renton AE, Kingsbury AE, Kumaran R, Kallis C, Vilariño-Güell C, O'Sullivan SS, Lees AJ, Revesz T, Wood NW, Holton JL.
LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: A morphological and quantitative study.
Neuropathol Appl Neurobiol. 2011 Jun 23.
PMID: 21696411
This antibody (previous batch) has been successfully used in IEM:
Alegre-Abarrategui J, Christian H, Lufino MM, Mutihac R, Venda LL, Ansorge O, Wade-Martins R.
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.
Hum Mol Genet. 2009 Nov 1;18(21):4022-34.
PMID: 19640926
This antibody (previous batch) has been successfully used in WB and IHC on Human:
Alegre-Abarrategui J, Ansorge O, Esiri M, Wade-Martins R.
LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease.
Neuropathol Appl Neurobiol. 2007 Oct 26.
PMID: 17971075