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Coronavirus

First identified in Humans in the 1960’s, coronaviruses belong to the family Coronaviridae; which is one of three RNA virus families within the order Nidovirales. The family is comprised of two subfamilies, Coronavirinae and Torovirinae; with members of Coronavirinae being divided into the four genera of alpha, beta, gamma and delta. Both coronaviruses and toroviruses are positive-stranded, enveloped RNA viruses, and were previously associated with mild respiratory symptoms. However, since 2002 the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) have both been shown to cause severe respiratory diseases. The most recent coronavirus strain identified SARS-coronavirus 2 (SARS-CoV-2), has resulted in the current global pandemic coronavirus disease 2019 (COVID-19).
A beta coronavirus, SARS-CoV-2 shares approximately 80% of its RNA sequence with SARS-CoV. It has four major structural proteins: the nucleocapsid protein (N), membrane protein (M), spike protein (S) and envelope protein (E). The spike protein (S) consists of two subunits, S1 and S2. The S1 subunit contains a receptor binding domain, which attaches to host cellular membrane receptors, such as Angiotensin converting enzyme 2 (ACE2). The S2 subunit allows for membrane fusion. In order to enter the host cell, the S protein requires priming by host proteases, such as TMPRSS2. The spike glycoproteins also give the virus its distinctive crown-like appearance and name. The nucleocapsid (N) protein is expressed mainly in the cytoplasm, and it’s binding to the CoV genome, allows it to be packaged into the ribonucleoprotein complex (capsid). The membrane (M) protein defines the shape of the viral envelope. Finally, the envelope (E) protein is integrated into the virion envelope.

Everest Biotech has been manufacturing anti-peptide and antigen affinity purified goat polyclonal antibodies since 2000. Please see our list of Covid-19 related antibodies below, and check out the LsBio products here: https://www.lsbio.com/research-areas/infectious-disease/coronavirus

Antibodies for Coronavirus

Everest code Principal name Applications Tested Species reactivity Size available
EB05382 Goat Anti-ADAM17 / TACE Antibody Pep-ELISA, WB, IHC Human, Mouse, Rat 100µg/200µl
EB07446 Goat Anti-AGTR1 / AT1 Antibody Pep-ELISA, WB Human, Mouse 100µg/200µl
EB09874 Goat Anti-AIM2 Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB09873 Goat Anti-AIM2 Antibody Pep-ELISA, WB Human 100µg/200µl
EB11894 Goat Anti-Aim2 (rodent) Antibody Pep-ELISA Mouse, Rat 100µg/200µl
EB07403 Goat Anti-CARD15 / NOD2 (Internal) Antibody Pep-ELISA, WB Human, Mouse, Rat 100µg/200µl
EB11976 Goat Anti-Cathepsin B (aa194-206) Antibody Pep-ELISA, IF Human, Rat, Dog, Pig, Cow 100µg/200µl
EB06816 Goat Anti-Cathepsin B Antibody Pep-ELISA, IF, IHC, FC Human, Mouse, Rat, Dog 100µg/200µl
EB11975 Goat Anti-Cathepsin B Antibody Pep-ELISA, WB, IF, IHC, FC Human 100µg/200µl
EB06650 Goat Anti-CCL3 and CCL3L1 Antibody Pep-ELISA Human 100µg/200µl
EB12534 Goat Anti-CD13 / ANPEP (aa79-91) Antibody Pep-ELSA, WB Human 100µg/200µl
EB12535 Goat Anti-CD13 / ANPEP Antibody Pep-ELISA, WB Human 100µg/200µl
EB10740 Goat Anti-CD28 Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB10741 Goat Anti-Cd28 (mouse) Antibody Pep-ELISA, WB Mouse 100µg/200µl
EB09701 Goat Anti-CD80 Antibody Pep-ELISA, WB Human 100µg/200µl
EB09883 Goat Anti-Cryopirin / NALP3 / NLRP3 Antibody Pep-ELISA Human, Mouse, Dog, Cow 100µg/200µl
EB09884 Goat Anti-Cryopirin / NALP3 / NLRP3 Antibody Pep-ELISA, IHC Human 100µg/200µl
EB08878 Goat Anti-CTLA + CTLB Antibody Pep-ELISA, WB, IHC Human, Mouse, Rat, Dog, Cow 100µg/200µl
EB12715 Goat Anti-DC-SIGN / CD209 Antibody Pep-ELISA, WB Human 100µg/200µl
EB08003 Goat Anti-DDX58 Antibody Pep-ELISA, FC, IF, IHC Human, Mouse 100µg/200µl
EB07835 Goat Anti-DPP4 / CD26 Antibody Pep-ELISA, WB Human, Mouse, Rat 100µg/200µl
EB11701 Goat Anti-G-CSF receptor Antibody Pep-ELISA Human 100µg/200µl
EB12862 Goat Anti-IFITM3 Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB12863 Goat Anti-IFITM3 (N terminus) Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB08349 Goat Anti-IFNAR2 Antibody Pep-ELISA, IHC Human 100µg/200µl
EB11757 Goat Anti-IL-10 (aa25-39) Antibody Pep-ELISA Human 100µg/200µl
EB07981 Goat Anti-LGP2 Antibody Pep-ELISA, WB Human 100µg/200µl
EB05965 Goat Anti-MDA5 / IFIH1 Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB07775 Goat Anti-MDA5 / Ifih1 (mouse) Antibody Pep-ELISA Mouse 100µg/200µl
EB06667 Goat Anti-MYD88 Antibody Pep-ELISA, WB, IHC, EIA Human, Mouse, Rat, Dog 100µg/200µl
EB12370 Goat Anti-OAS1 Antibody Pep-ELISA, WB Human 100µg/200µl
EB12373 Goat Anti-OAS2 (aa357-371) Antibody Pep-ELISA, WB, IHC Human 100µg/200µl
EB12372 Goat Anti-OAS2 Antibody Pep-ELISA, WB Human 100µg/200µl
EB12375 Goat Anti-OAS3 Antibody Pep-ELISA, WB Human 100µg/200µl
EB07379 Goat Anti-STAT3 Antibody Pep-ELISA, WB, IHC Human, Mouse, Rat, Dog 100µg/200µl
EB05073 Goat Anti-STAT3 (isoform 1 and 2) Antibody Pep-ELISA, IHC, IF, FC Human, Mouse, Rat, Dog, Pig, Cow 100µg/200µl
EB12431 Goat Anti-TICAM-1 / TRIF Antibody Pep-ELISA, WB Human, Mouse, Rat, Dog, Pig, Cow 100µg/200µl
EB09441 Goat Anti-TLR4 / CD284 Antibody Pep-ELISA, IF Human, Mouse, Rat, Dog, Cow, Pig, Sheep 100µg/200µl
EB08219 Goat Anti-TMPRSS2 Antibody Pep-ELISA, WB Human 100µg/200µl
EB11287 Goat Anti-TRIM11 (aa249-263) Antibody Pep-ELISA, WB, IHC Human, Pig, Cow 100µg/200µl
EB05908 Goat Anti-TRIM11 Antibody Pep-ELISA, IHC Human 100µg/200µl
EB07084 Goat Anti-TRIM5 / RNF88 (alpha isoform) Antibody Pep-ELISA, IHC Human 100µg/200µl
EB05932 Goat Anti-TRIM5 / RNF88 Antibody Pep-ELISA, WB Human 100µg/200µl
EB08557 Goat Anti-XBP1 / TREB5 Antibody Pep-ELISA, WB, IF, IHC Human, Mouse, Rat, Dog 100µg/200µl
EB2ND-002-AP Rabbit anti-goat IgG antibody AP Conjugated - 1mg
EB2ND-001-HRP Rabbit anti-Goat IgG antibody HRP Conjugated - 1mg